The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: cis-Dichlorobis(pyridine)platinum(II)( cas:15227-42-6 ) is researched.Quality Control of cis-Dichlorobis(pyridine)platinum(II).Kotowski, M.; Palmer, D. A.; Kelm, H. published the article 《Volumes of activation for the substitution reactions of cis- and trans-[PtL2(Cl)X] with pyridine in various solvents》 about this compound( cas:15227-42-6 ) in Inorganic Chemistry. Keywords: platinum complex substitution kinetics pyridine; volume activation platinum complex substitution; solvent effect platinum complex substitution. Let’s learn more about this compound (cas:15227-42-6).
The pressure dependence of the 2nd-order rate constant for the substitution of pyridine for Cl in trans-[Pt(py)2(Cl)(NO2)] was measured in the solvents nitromethane, methanol, ethanol, and dichloromethane. The resp. ΔV*exptl. values were calculated to be -6.2 ± 0.4 at 10°, -8.8 ± 0.6 at 25°, -13.1 ± 0.8 at 25°, and -19.8 ± 1.7 cm3 mol-1 att 25°. The ΔVexptl. values for the corresponding reactions of cis-[Pt(py)2(Cl)(NO2)] and trans-[Pt(PEt3)2Cl2] in methanol at 25° are -5.5 ± 0.5 and -13.6 ± 0.8 cm3 mol-1, resp. These ΔV*exptl.’s were found to be only slightly temperature dependent. The activation parameters ΔH*2 and ΔS*2 were also determined for each reaction. The volume change associated with the partial formation of the Pt-pyridine bond was estimated to be -4 ± 1 cm3 mol-1. A qual. explanation of the solvent dependence of ΔV*exptl. is also given.
In addition to the literature in the link below, there is a lot of literature about this compound(cis-Dichlorobis(pyridine)platinum(II))Quality Control of cis-Dichlorobis(pyridine)platinum(II), illustrating the importance and wide applicability of this compound(15227-42-6).
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem