The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: Picolinamide(SMILESS: O=C(N)C1=NC=CC=C1,cas:1452-77-3) is researched.HPLC of Formula: 882562-40-5. The article 《Ionic liquid catalysed aerobic oxidative amidation and thioamidation of benzylic amines under neat conditions》 in relation to this compound, is published in Green Chemistry. Let’s take a look at the latest research on this compound (cas:1452-77-3).
Tetrabutylammonium hydroxide (TBAOH) was discovered as a highly efficient and green catalyst for aerobic oxidation of the α-methylene carbon of primary amines as well as benzylic groups RCH2NH2 (R = Ph, pyren-1-yl, thiophene-2-yl, etc.) into the corresponding amides RC(O)NH2 and ketones R1C(O)C6H5 [R1 = Ph, pyridin-2-yl, C6H5C(O)] and 9H-fluoren-9-one under neat conditions. Ionic liquid TBAOH catalyzed aerobic oxidation of benzyl amines to benzamides and with elemental sulfur was described; and the corresponding benzylbenzothioamides RC(S)NHCH2R were obtained under metal-free, oxidant-free and base-free conditions. Applicability at the gram scale for the synthesis of the desired amides/ketones is also demonstrated with the present protocol.
Although many compounds look similar to this compound(1452-77-3)Recommanded Product: 1452-77-3, numerous studies have shown that this compound(SMILES:O=C(N)C1=NC=CC=C1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem