170097-67-3, 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid is a tetrahydroisoquinoline compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,170097-67-3
To a solution of 2-{[(1 ,1-dimethylethyl)oxy]carbonyl}-1 ,2,3,4-tetrahydro-6- isoquinolinecarboxylic acid (33 mg, 0.12 mmol), HOBt (19 mg, 0.14 mmol), EDCI (26 mg, 0.14 mmol) and triethylamine (14 mg, 14 mmol) in DCM (3 ml.) was added 4-[(3- nitrophenyl)methyl]-1 ,3-thiazol-2-amine (30 mg, 0.12 mmol) and the resulting mixture was stirred at room temperature for 2 days. The organic phase was washed successively with water, with a 1 N solution of sodium hydroxide, with brine, dried over Na2SO4, filtered and evaporated under reduced pressure. The residue was purified by flash column chromatography eluting with DCM / MeOH: 98 / 2 to give the title compound as a pale yellow oil (30 mg, 52%). LC/MS: m/z 495 (M+H)+, Rt : 3.68 min.
As the paragraph descriping shows that 170097-67-3 is playing an increasingly important role.
Reference£º
Patent; SMITHKLINE BEECHAM CORPORATION; WO2009/150196; (2009); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem