Wiczk, Wieslaw’s team published research in Journal of the American Chemical Society in 118 | CAS: 142335-42-0

Journal of the American Chemical Society published new progress about 142335-42-0. 142335-42-0 belongs to tetrahydroisoquinoline, auxiliary class Tetrahydroisoquinoline,Chiral,Carboxylic acid,Amide,Alcohol, name is (S)-2-(tert-Butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, and the molecular formula is C10H12O5, HPLC of Formula: 142335-42-0.

Wiczk, Wieslaw published the artcilePhotophysics of 7-hydroxytetrahydroisoquinoline-3-carboxylic acid and its derivatives, HPLC of Formula: 142335-42-0, the publication is Journal of the American Chemical Society (1996), 118(35), 8300-8307, database is CAplus.

Derivatives of 7-hydroxytetrahydroisoquinoline-3-carboxylic acid {Tic(OH) [I]}, a conformationally restricted analog of tyrosine, were synthesized for photophys. studies aimed at elucidating the nature of tyrosine fluorescence and its decay. The derivatives included Ac-Tic(OH) [II], Ac-Tic(OH)-NHMe [III], Tic(OH)-NHMe [IV], Ala-Tic(OH) [V], Ac-Ala-Tic(OH) [VI], and Tic(OH)-Gly-NH2 [VII]. For the I-IV derivatives the N-methylamide was more effective quencher than the acetyl group. For the V-VII derivatives the highest quenching of fluorescence of the phenolic chromophore was observed in Ala-Tic(OH). The simple Tic(OH) derivatives I-IV were also the subject of theor. studies (MOPAC 93). The obtained thermodn. parameters (MOPAC calculations) and the fluorescence components were discussed on the basis of the rotamer theory in order to explain the participation of an individual rotamer in the complex process of the fluorescence decay of tyrosine.

Journal of the American Chemical Society published new progress about 142335-42-0. 142335-42-0 belongs to tetrahydroisoquinoline, auxiliary class Tetrahydroisoquinoline,Chiral,Carboxylic acid,Amide,Alcohol, name is (S)-2-(tert-Butoxycarbonyl)-7-hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, and the molecular formula is C10H12O5, HPLC of Formula: 142335-42-0.

Referemce:
https://en.wikipedia.org/wiki/Tetrahydroisoquinoline,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem