Iridium-Catalyzed Enantioselective α-C(sp3)-H Borylation of Azacycles was written by Chen, Lili;Yang, Yuhuan;Liu, Luhua;Gao, Qian;Xu, Senmiao. And the article was included in Journal of the American Chemical Society in 2020.Product Details of 207451-81-8 This article mentions the following:
Herein is reported an iridium-catalyzed enantioselective α-C(sp3)-H borylation of a wide range of azacycles. The combination of an iridium precursor and a chiral pyridyl 1,3,2-diazaborole bidentate boryl ligand has been shown to effectively differentiate enantiotopic methylene C-H bonds from a single carbon center, affording a variety of synthetically useful azacycles, e.g. I, from readily available starting materials with good to excellent enantioselectivities. In the experiment, the researchers used many compounds, for example, 7-Methyl-1,2,3,4-tetrahydroisoquinoline (cas: 207451-81-8Product Details of 207451-81-8).
7-Methyl-1,2,3,4-tetrahydroisoquinoline (cas: 207451-81-8) belongs to tetrahydroisoquinoline derivatives. Tetrahydroisoquinoline, as a secondary amine, tetrahydroisoquinoline has weakly basic properties and forms salts with strong acids. Arene/Ru/TsDPEN complexes bearing a heterocyclic group catalyze the asymmetric transfer hydrogenation (ATH) of 1-aryl dihydroisoquinolines (DHIQs) to provide tetrahydroisoquinolines of high enantiomeric excess.Product Details of 207451-81-8
Referemce:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem