Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 17680-55-6, Name is 7-Bromo-1,2,3,4-tetrahydroisoquinoline. In a document type is Article, introducing its new discovery., 17680-55-6
Lactam and oxazolidinone derived potent 5-hydroxytryptamine 6 receptor antagonists
Lactam and oxazolidinone derived potent 5-hydroxytryptamine 6 (5-HT 6) receptor antagonists have been disclosed. One potent member from the lactam series, racemic compound 14 (Ki of 2.6 nM in binding assay, IC50 of 15 nM in functional cAMP antagonism assay) was separated into corresponding enantiomers that displayed the effect of chirality on binding potency (Ki of 1.6 nM and 3000 nM, respectively). The potent enantiomer displayed an IC50 of 8 nM in cAMP antagonism assay, selectivity against a number of family members as well as brain permeability in rats after 6 h post oral administration.
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Reference£º
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem