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Sequence catalysis merging photoredox catalysis (PC) and nucleophilic catalysis (NC) has been realized for the direct sp3 C-H acroleination of N-aryl-tetrahydroisoquinoline (THIQ). The reaction was performed under very mild conditions and afforded products in 50-91% yields. A catalytic asymmetric variant was proved to be successful with moderate enantioselectivities (up to 83 : 17 er).

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A controllable mono- and di-multifluoroarylation of acyclic and cyclic N-aryl amines with aryl fluorides by photocatalyzed dual C(sp3)?H/C(sp2)?F functionalization has been developed, providing new access to a wide array of valuable alpha-fluoroarylated amines. In addition, the one-pot consecutive hetero-di-multifluoroarylation of N-aryl pyrrolidines and N,N-dimethylanilines was achieved with high to excellent diastereoselectivity. This new defluorinative C(sp3)?C(sp2) coupling is distinguished by a broad scope, good regioselectivity, and mild conditions as well as gram-scale and late-stage applicability, and thus constitutes a significant advance in the arylation of unactivated C(sp3)?H bonds with aryl fluorides.

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This paper reports a useful method for molecular-iodine-catalyzed aerobic photooxidative C-C bond formation between tertiary amines and carbon nucleophiles. This reaction provides a practical method for C-C bond formation through the use of molecular iodine, harmless visible light irradiation, and molecular oxygen as the terminal oxidant. The Royal Society of Chemistry 2013.

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H/D exchanges of arylmethyl amines and nitrogen heterocycles were conveniently achieved with KOt-Bu/DMSO-d6. The method is also applicable for phenyl benzyl ethers, diarylmethanes, and alkyl arenes. These H/D exchange reactions are suggested to proceed via a free radical pathway.

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For converting a homogeneous synthetic chemistry reaction to a heterogeneous one, using nanocatalysts, it is essential to investigate the underlying principles and the associated dominant factors of methodologies between inorganic nanoparticles and organic substrates. Here it is reported that novel, hydrothermally synthesized ruthenium (Ru) nanoparticles performed differently in molecular oxygen activation via single electron transfer for cross-dehydrogenative-coupling reactions, following a volcano shaped relationship between their oxidation levels and catalytic activity. Characterizations and a systematic mechanism study indicated that Ru3+ sites contributed to more superoxo- or peroxo-like species being formed from molecular oxygen on Ru nanoparticles with a moderate oxidation level, and the Ru3+ were the highly active species which accelerate this cross-dehydrogenative-coupling reaction via single electron transfer.

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A highly efficient sp3-sp3 carbon-carbon bond formation system was developed for the aerobic ruthenium-catalyzed oxidative cross-dehydrogenative coupling reaction between tertiary amines and sp3 C-H compounds in the presence of RuCl3/O2, thus giving the corresponding alpha-functionalized amines. Compared with the reported method, H2O2 or tBuOOH was replaced successfully by economical and facile oxygen as the oxidant. Three types of activated C-H bonds for pronucleophiles were evaluated in this system. All these features combined are in accordance with important prospective green chemistry aspects.

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A novel 3D porous metal-organic framework was constructed from imidazole carboxylate linkers and copper(ii) nodes, which in situ generates multiple active CuII sites in the nanosized channel walls for highly efficient cross dehydrogenative coupling reaction between 1,2,3,4-tetrahydroisoquinoline derivatives and nitroalkanes that are superior to the simple copper salts.

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CuBr-catalyzed oxidative difluoromethylation of readily available tertiary amines with difluoroenol silyl ethers was performed under mild conditions to afford beta-amine-a,a-difluoro ketones.

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The oxidative C-C bond formations between Csp3-H bond adjacent to nitrogen and Csp3-H bond of nitroalkanes are catalyzed efficiently by magnetically recoverable iron nanoparticles using oxygen. The catalyst can be magnetically removed and recycled easily for nine times without decreasing activity. Georg Thieme Verlag Stuttgart.

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Chemical Research Letters, May 2021. Computed Properties of C15H15N, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.3340-78-1, Name is 2-Phenyl-1,2,3,4-tetrahydroisoquinoline, molecular formula is C15H15N. In a Article,once mentioned of 3340-78-1

Cooperative catalysts: An enantioselective and direct oxidative coupling of aldehydes to tertiary amines to give beta-amino alcohols is described. Catalyzed by copper(II), the reaction proceeds to give a racemic mixture of products; however, by using a combination of copper(II) and a chiral amine catalyst, the reaction gives the desired products with high enantioselectivity (see scheme).

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Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem