Category: 693-67-4

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 693-67-4, is researched, SMILESS is CCCCCCCCCCCBr, Molecular C11H23BrJournal, Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov’t, Research Support, U.S. Gov’t, Non-P.H.S., Biomacromolecules called Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes, Author is Buzzacchera, Irene; Xiao, Qi; Han, Hong; Rahimi, Khosrow; Li, Shangda; Kostina, Nina Yu.; Toebes, B. Jelle; Wilner, Samantha E.; Moller, Martin; Rodriguez-Emmenegger, Cesar; Baumgart, Tobias; Wilson, Daniela A.; Wilson, Christopher J.; Klein, Michael L.; Percec, Virgil, the main research direction is dendrimer dendrimersome.Quality Control of 1-Bromoundecane.

Natural, including plant, and synthetic phenolic acids are employed as building blocks for the synthesis of constitutional isomeric libraries of self-assembling dendrons and dendrimers that are the simplest examples of programmed synthetic macromols. Amphiphilic Janus dendrimers are synthesized from a diversity of building blocks including natural phenolic acids. They self-assemble in water or buffer into vesicular dendrimersomes employed as biol. membrane mimics, hybrid and synthetic cells. These dendrimersomes are predominantly uni- or multilamellar vesicles with size and polydispersity that is predicted by their primary structure. However, in numerous cases, unilamellar dendrimersomes completely free of multilamellar assemblies are desirable. Here, we report the synthesis and structural anal. of a library containing 13 amphiphilic Janus dendrimers containing linear and branched alkyl chains on their hydrophobic part. They were prepared by an optimized iterative modular synthesis starting from natural phenolic acids. Monodisperse dendrimersomes were prepared by injection and giant polydisperse by hydration. Both were structurally characterized to select the mol. design principles that provide unilamellar dendrimersomes in higher yields and shorter reaction times than under previously used reaction conditions. These dendrimersomes are expected to provide important tools for synthetic cell biol., encapsulation, and delivery.

If you want to learn more about this compound(1-Bromoundecane)Quality Control of 1-Bromoundecane, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(693-67-4).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

COA of Formula: C11H23Br. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Polar functional group-containing glycolipid CD1d ligands modulate cytokine-biasing responses and prevent experimental colitis.

The MHC class I-like mol. CD1d is a nonpolymorphic antigen-presenting glycoprotein, and its ligands include glycolipids, such as α-GalCer. The complexes between CD1d and ligands activate natural killer T cells by T cell receptor recognition, leading to the secretion of various cytokines (IFN-γ, IL-4, IL-17A, etc.). Herein, we report structure-activity relationship studies of α-GalCer derivatives containing various functional groups in their lipid acyl chains. Several derivatives have been identified as potent CD1d ligands displaying higher cytokine induction levels and/or unique cytokine polarization. The studies also indicated that flexibility of the lipid moiety can affect the binding affinity, the total cytokine production level and/or cytokine biasing. Based on our immunol. evaluation and investigation of physicochem. properties, we chose bisamide- and Bz amide-containing derivatives 2 and 3, and evaluated their in vivo efficacy in a DSS-induced model of ulcerative colitis. The derivative 3 that exhibits Th2- and Th17-biasing responses, demonstrated significant protective effects against intestinal inflammation in the DSS-induced model, after a single i.p. injection.

If you want to learn more about this compound(1-Bromoundecane)COA of Formula: C11H23Br, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(693-67-4).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Even-Odd Alkyl Chain-Length Alternation Regulates Oligothiophene Crystal Structure, published in 2019-09-10, which mentions a compound: 693-67-4, Name is 1-Bromoundecane, Molecular C11H23Br, Safety of 1-Bromoundecane.

Alkyl chains of varied length and steric bulk are generally appended to π-conjugated chromophores to increase solubility These alkyl chains also regulate many aspects of the solid-state packing and, in turn, resultant electronic and optical properties of organic semiconductors, yet there remains little understanding as to how these moieties govern such characteristics. Here, we report on a series of (2,5-bis(3-alkylthiophen-2-yl) thieno[3,2-b]thiophenes) (BTTT) monomers where the single-crystal packing configurations and m.ps. alternate as a function of whether the alkyl side chains have an even or odd number of carbon atoms. When the alkyl chains contain an even number of carbon atoms, the mols. predominantly crystallize with the BTTT units of the stacked lamellae aligned in the same direction. In contrast, when the number of carbon atoms is odd, alternating lamellae are twisted with respect to their neighbors, i.e. the BTTT moieties in one layer are aligned in an orthogonal-like fashion to those in its neighboring lamellae, and the crystal m.ps. tend to be higher than those with the even-numbered alkyl chains. With d. functional theory calculations and geometric analyses, the variations in crystal structure and thus the differences in phys. properties are rationalized by an oscillating interlayer interaction that is a function of alkyl side chain atom count and length. This study characterizes an extreme case of an organic semiconductor crystal packing alternation to highlight the effect of even-odd assembly as an underutilized and under-reported handle for tuning the mol. packing of organic semiconductor materials.

If you want to learn more about this compound(1-Bromoundecane)Safety of 1-Bromoundecane, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(693-67-4).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-Bromoundecane( cas:693-67-4 ) is researched.Computed Properties of C11H23Br.Wang, Senlin; Wu, Hongshuai; Chen, Fanghui; Zhang, Yu; Zhang, Yuchen; Sun, Baiwang published the article 《The antitumor activity of 4,4′-bipyridinium amphiphiles》 about this compound( cas:693-67-4 ) in RSC Advances. Keywords: alveolar basal carcinoma cell bipyridinium amphiphile antitumor SAR. Let’s learn more about this compound (cas:693-67-4).

A series of 4,4′-bipyridinium amphiphiles, compounds I [n = 8-16] were synthesized and their anticancer activities were further evaluated. MTT assay showed that the cytotoxicity first increased and then decreased with the growth of carbon chains (8-16 C) at both ends of bipyridyl. Specifically, compounds with saturated carbon chains consisting of 13 carbons at both ends of bipyridyl displayed the best cell inhibitory activity with IC50 values in the low-micromolar range, which were even superior to that of cisplatin, against all the tested human cancer cells and cisplatin-resistant A549 cancer cells in vitro. In addition, compound I [n = 13] could evidently arrest the G2/M phase of the cell cycle in a dose-dependent manner. Moreover, this study demonstrates the potent performance of compound I [n = 13] in cell growth inhibition and apoptosis induction via a conceivable approach of membrane damage.

If you want to learn more about this compound(1-Bromoundecane)Computed Properties of C11H23Br, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(693-67-4).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Inuki, Shinsuke; Hirata, Natsumi; Kashiwabara, Emi; Kishi, Junichiro; Aiba, Toshihiko; Teratani, Toshiaki; Nakamura, Wataru; Kojima, Yoshimi; Maruyama, Toru; Kanai, Takanori; Fujimoto, Yukari researched the compound: 1-Bromoundecane( cas:693-67-4 ).Recommanded Product: 1-Bromoundecane.They published the article 《Polar functional group-containing glycolipid CD1d ligands modulate cytokine-biasing responses and prevent experimental colitis》 about this compound( cas:693-67-4 ) in Scientific Reports. Keywords: SAR glycolipid ligand polar functional group cytokine biasing colitis. We’ll tell you more about this compound (cas:693-67-4).

The MHC class I-like mol. CD1d is a nonpolymorphic antigen-presenting glycoprotein, and its ligands include glycolipids, such as α-GalCer. The complexes between CD1d and ligands activate natural killer T cells by T cell receptor recognition, leading to the secretion of various cytokines (IFN-γ, IL-4, IL-17A, etc.). Herein, we report structure-activity relationship studies of α-GalCer derivatives containing various functional groups in their lipid acyl chains. Several derivatives have been identified as potent CD1d ligands displaying higher cytokine induction levels and/or unique cytokine polarization. The studies also indicated that flexibility of the lipid moiety can affect the binding affinity, the total cytokine production level and/or cytokine biasing. Based on our immunol. evaluation and investigation of physicochem. properties, we chose bisamide- and Bz amide-containing derivatives 2 and 3, and evaluated their in vivo efficacy in a DSS-induced model of ulcerative colitis. The derivative 3 that exhibits Th2- and Th17-biasing responses, demonstrated significant protective effects against intestinal inflammation in the DSS-induced model, after a single i.p. injection.

If you want to learn more about this compound(1-Bromoundecane)Recommanded Product: 1-Bromoundecane, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(693-67-4).

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Name: 1-Bromoundecane. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Synthesis and microbiological properties of novel bis-quaternary ammonium compounds based on 4,4′-oxydiphenol spacer. Author is Vereshchagin, Anatoly N.; Frolov, Nikita A.; Konyuhova, Valeria Yu.; Hansford, Karl A.; Egorov, Mikhail P..

Novel gemini (tail-head-spacer-head-tail) bis-quaternary ammonium compounds I [n = 7, 8, 9, etc.] with a 4,4′-oxydiphenol spacer between two pyridinium heads were synthesized and compared with commonly used antiseptics such as benzalkonium chloride and chlorhexidine gluconate. Analogs bearing C8H17, C9H19 and C10H21 aliphatic groups displayed potent broad spectrum in-vitro activity against five bacterial strains and two fungi, with min. inhibitory concentrations relatively independent of the counter ion.

In some applications, this compound(693-67-4)Name: 1-Bromoundecane is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Effects of Broussonetia papyrifera-fermented feed on the growth performfermentedance and muscle quality of Hu sheep, the main research direction is Broussonetia papyrifera fermentation feed muscle quality Hu sheep.COA of Formula: C11H23Br.

This study aims to determine the effect of adding different proportions of Broussonetia papyrifera (BP)-fermented feed on Hu sheep. A total of 40 male Hu sheep (weighting 20.6 ± 2.20 kg) were collected and then divided into group I, II, III, and IV, with 0%, 5%, 10%, and 15% of BP-fermented feed to based diet, resp. After the trial period of 10 and 50 d, the sheep were slaughtered by conventional methods for the chem. analyses. It showed that adding 10% fermented feed could significantly increase the growth performance of the Hu sheep. Adding the fermented feed can improve the protein level, main flavor amino acid content, and fatty acid in the muscle. Based on the headspace solid-phase microextraction and gas chromatog. – mass spectrometry methods, a total of 125, 120, 119, and 117 kinds of volatile compounds were identified in group I, II, III, and IV, among which the relative content of the acid compound, ester compound, ketone compound, and aldehydes in group II, III, and IV were higher than that in control group, resp. Addition of BP-fermented feed could significantly improve growth performance and meat quality of Hu sheep.

In some applications, this compound(693-67-4)COA of Formula: C11H23Br is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

HPLC of Formula: 693-67-4. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Monodisperse micelles composed of poly(ethylene glycol) attached surfactants: platonic nature in a macromolecular aggregate. Author is Lee, Ji Ha; Matsumoto, Hayata; Fujii, Shota; Takahashi, Rintaro; Sakurai, Kazuo.

Among the many studies on micelles, dating back more than 100 years, we first found a series of monodisperse micelles: spherical micelles made from calix[4]arene surfactants exhibited monodispersity in aggregation number (Nagg) with values of 4, 6, 8, 12, and 20. We named these Platonic micelles because these values coincided with the face numbers of the Platonic solids. The preferred Nagg values were explained in relation to the math. Tammes problem: how to obtain the best coverage of a sphere surface with multiple identical circles. In this paper, we synthesized poly(ethylene glycol)-attached surfactants and carried out small-angle X-ray scattering (SAXS) and anal. ultracentrifugation (AUC) to determine the Nagg. We found that these polymeric surfactants also formed monodispersed micelles and Nagg discontinuously increased from 20 to 24, and then 32 with increasing the alkyl carbon numbers from 9 to 11 continuously. The determined Nagg was greater than 20 and the Platonic solid numbers We assumed that the preferred Nagg values could be explained in relation to the Tammes problem as well.

In some applications, this compound(693-67-4)HPLC of Formula: 693-67-4 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of the Serbian Chemical Society called Novel (-)-goniofufurone mimics: Synthesis, antiproliferative activity and SAR analysis, Author is Zelenovic, Bojana Sreco; Kekezovic, Sladjana; Popsavin, Mirjana; Kojic, Vesna; Benedekovic, Goran; Popsavin, Velimir, which mentions a compound: 693-67-4, SMILESS is CCCCCCCCCCCBr, Molecular C11H23Br, Application In Synthesis of 1-Bromoundecane.

Divergent syntheses of novel (-)-goniofufurone mimics with an alko-xymethyl group as the side chain have been accomplished from D-glucose in nine synthetic steps and in overall yields 6.7-8.7%. Their in vitro antiproliferative activity was evaluated against eight human tumor cell lines as well as a single normal cell line. All analogs demonstrated powerful to good antiproliferative effects toward all malignant cell lines under evaluation. Against the HL-60 cell line, all mimics showed increased activities being 27- to 1604-fold more potent than the lead compound, (-)-goniofufurone. Remarkably, the majority of synthesized analogs displayed higher or similar activity to the com. antitumor agent doxorubicin (DOX) against A549 cell line. The most potent compound exhibited 196-fold stronger cytotoxicity than DOX in the culture of this cell line.

In some applications, this compound(693-67-4)Application In Synthesis of 1-Bromoundecane is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Ishida, Takashi; Yoshimura, Haruna; Takekawa, Masatsugu; Higaki, Takumi; Ideue, Takashi; Hatano, Masaki; Igarashi, Masayuki; Tani, Tokio; Sawa, Shinichiro; Ishikawa, Hayato published the article 《Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules》. Keywords: kumamonamide preparation herbicide plant microtubule actin filament SAR.They researched the compound: 1-Bromoundecane( cas:693-67-4 ).Application of 693-67-4. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:693-67-4) here.

In the present study, authors discovered a novel N-alkoxypyrrole compound, kumamonamide from Streptomyces werraensis MK493-CF1 and established a total synthesis procedure. Resulted in the bioactivity assays, it was found that kumamonamic acid, a synthetic intermediate of kumamonamide, is a potential plant growth inhibitor. Further, various derivatives of kumamonamic acid are developed, including a kumamonamic acid nonyloxy derivative (KAND), which displayed high herbicidal activity without adverse effects on HeLa cell growth. Authors also detected that kumamonamic acid derivatives disturb plant microtubules; and addnl., that KAND affected actin filaments and induced cell death. These multifaceted effects differ from those of known microtubule inhibitors, suggesting a novel mode of action of kumamonamic acid, which represents an important lead for the development of new herbicides.

In some applications, this compound(693-67-4)Application of 693-67-4 is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem