Tag: M.W:200-300

Li, Jie; Li, Xiang; Yuan, Yan; Wang, Qi; Xie, Lisi; Dai, Yunlu; Wang, Wenjun; Li, Lin; Lu, Xiaomei; Fan, Quli; Huang, Wei published the article 《Efficient Polysulfide-Based Nanotheranostics for Triple-Negative Breast Cancer: Ratiometric Photoacoustics Monitored Tumor Microenvironment-Initiated H2S Therapy》. Keywords: polysulfide nanotheranostic breast cancer photoacoustic tumor microenvironment hydrogen sulfide; hydrogen sulfide; polysulfide; ratiometric photoacoustics; theranostics; triple-negative breast cancer.They researched the compound: 1-Bromoundecane( cas:693-67-4 ).Application of 693-67-4. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:693-67-4) here.

The incidence of triple-neg. breast cancer (TNBC) is difficult to predict, and TNBC has a high mortality rate among women worldwide. A theranostics approach is developed for TNBC with ratiometric photoacoustic monitored thiol-initiated hydrogen sulfide (H2S) therapy. The ratiometric photoacoustic (PA) probe (CY) with a thiol-initiated H2S donor (PSD) to form a nanosystem (CY-PSD nanoparticles) is integrated. In this theranostics approach, H2S generated from PSD is sensed by CY based on ratiometric PA signals, which simultaneously pinpoints the tumor region. Addnl., H2S is cytotoxic toward TNBC cells (MDA-MB 231), showing a tumor inhibition rate of 63%. To further verify its pharmacol. mechanism, proteomics anal. was performed on tumors treated with CY-PSD nanoparticles. Cells are killed by the significant mitochondrial dysfunction via suppressed energy supply and apoptosis initiation. Besides, the observed inhibition of oxidative stress also generates the cytotoxicity. Significant Kyoto Encyclopedia of Genes Genomes pathways related to TNBC are inhibited. This H2S theranostics approach updates the current anticancer therapies which brings promise for women suffering malignant breast cancer.

Compounds in my other articles are similar to this one(1-Bromoundecane)Application of 693-67-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and biological evaluation of novel bis-quaternary ammonium compounds with p-terphenyl spacer, published in 2020-07-31, which mentions a compound: 693-67-4, mainly applied to quaternary ammonium compound terphenyl spacer preparation SAR; antibacterial antifungal cytotoxicity human, Related Products of 693-67-4.

Bis-quaternary ammonium compounds I·2 Br- [R = H(CH2)n; n = 7, 8, 9, 10, 11] with a p-terphenyl spacer between two pyridinium heads were synthesized. I·2 Br- (n = 8) was superior to the known benzalkonium chloride, miramistin and chlorhexidine bisgluconate in its MIC values against five pathogenic bacteria.

Compounds in my other articles are similar to this one(1-Bromoundecane)Related Products of 693-67-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-Bromoundecane(SMILESS: CCCCCCCCCCCBr,cas:693-67-4) is researched.Related Products of 693-67-4. The article 《Antiferroptotic Activity of Phenothiazine Analogues: A Novel Therapeutic Strategy for Oxidative Stress Related Disease》 in relation to this compound, is published in ACS Medicinal Chemistry Letters. Let’s take a look at the latest research on this compound (cas:693-67-4).

The synthesis of series of lipophilic phenothiazine analogs I (n = 4, 5, 6, 8) that potently inhibit ferroptosis was reported in the present study. The most promising compounds I exhibited an improved protection compared to the parent phenothiazine against erastin- and RSL3-induced ferroptotic cell death. These analogs have equivalent or better potency than ferrostatin-1 (Fer-1) and liproxstatin-1 (Lip-1), which are among the most potent inhibitors of this regulated cell death described so far. They represent novel lead compounds with therapeutic potential in relevant ferroptosis-driven disease models such as FRDA.

Compounds in my other articles are similar to this one(1-Bromoundecane)Recommanded Product: 1-Bromoundecane, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Product Details of 693-67-4. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about 4-Carboalkoxylated Polyvalerolactones from Malic Acid: Tough and Degradable Polyesters. Author is Fahnhorst, Grant W.; De Hoe, Guilhem X.; Hillmyer, Marc A.; Hoye, Thomas R..

Eight 4-carboalkoxyvalerolactones (CRVLs), varying in the composition of their alkyl (R) side chains, were synthesized from malic acid and subjected to ring-opening transesterification polymerization (ROTEP) using di-Ph phosphate [DPP, (PhO)2PO2H] as a catalyst. Each CRVL produced a semicrystalline poly(4-carboalkoxyvalerolactone) (PCRVL), and the nature of the R group impacted the thermal transitions of these polyesters. Bulk polymerizations at 70°C allowed for preparation of high molar mass samples that contained small amounts of branching, as evidenced by 1H NMR spectroscopy, MALDI spectrometry, size-exclusion chromatog., and eliminative degradation Tensile testing of these lightly branched, high molar mass samples revealed that these polyesters are tough (tensile toughness values up to 88 ± 33 MJ•m-3) and have Young’s moduli (E) up to 186 ± 13 MPa. The acid- and base-catalyzed hydrolytic degradation of the PCRVLs was quant. monitored using total organic carbon anal., and effect of the alkyl chain length on PCRVL hydrolysis rate was determined Finally, the Me ester variant of these malic acid-derived thermoplastics is known to be chem. recyclable.

Compounds in my other articles are similar to this one(1-Bromoundecane)Product Details of 693-67-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 57399-11-8, is researched, SMILESS is C#CC1=CC=C(C2=CC=C(Cl)C=C2)C=C1, Molecular C14H9ClJournal, Article, Research Support, Non-U.S. Gov’t, Journal of Medicinal Chemistry called Synthesis and Antiplasmodial Activity of New Indolone N-Oxide Derivatives, Author is Nepveu, Francoise; Kim, Sothea; Boyer, Jeremie; Chatriant, Olivier; Ibrahim, Hany; Reybier, Karine; Monje, Marie-Carmen; Chevalley, Severine; Perio, Pierre; Lajoie, Barbora H.; Bouajila, Jalloul; Deharo, Eric; Sauvain, Michel; Tahar, Rachida; Basco, Leonardo; Pantaleo, Antonella; Turini, Francesco; Arese, Paolo; Valentin, Alexis; Thompson, Eloise; Vivas, Livia; Petit, Serge; Nallet, Jean-Pierre, the main research direction is indolone oxide preparation antiplasmodial activity.Computed Properties of C14H9Cl.

A series of 66 new indolone-N-oxide derivatives, e.g. I, was synthesized with three different methods. Compounds were evaluated for in vitro activity against CQ-sensitive (3D7), CQ-resistant (FcB1), and CQ and pyrimethamine cross-resistant (K1) strains of Plasmodium falciparum (P.f.), as well as for cytotoxic concentration (CC50) on MCF7 and KB human tumor cell lines. Compound II (5-methoxy-indolone-N-oxide analog) had the most potent antiplasmodial activity in vitro (<3 nM on FcB1 and = 1.7 nM on 3D7) with a very satisfactory selectivity index (CC50 MCF7/IC50 FcB1: 14623; CC50 KB/IC50 3D7: 198823). In in vivo experiments, compound I (dioxymethylene derivatives of the indolone-N-oxide) showed the best antiplasmodial activity against Plasmodium berghei, 62% inhibition of the parasitemia at 30 mg/kg/day. Compounds in my other articles are similar to this one(4-Chloro-4'-ethynyl-1,1'-biphenyl)Computed Properties of C14H9Cl, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Coumarin dimers of benzidine and phenylenediamine cores: synthesis, characterisation and mesomorphic properties.Recommanded Product: 693-67-4.

Three new homologous series of coumarin heterocycles-derived mesogens I (X = biphenyl-4,4′-diyl, benzene-1,4-diyl, 3,3′-dimethoxy-biphenyl-4,4′-diyl; R = C6H13, C10H21, C14H29, etc.) have been synthesized and characterized. The sym. dimers of coumarin contain two Schiff base moieties as connecting groups with Ph or biphenyl central cores. Thermal, mesophase behaviors and textural types were studied by DSC and POM instrumentations. The nematic mesophase was enhanced prominently for most of the compounds, and appeared in relatively medium to long alkyl chain at both terminals of the mols.

Compounds in my other articles are similar to this one(1-Bromoundecane)Recommanded Product: 693-67-4, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Formula: C11H23Br. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Even-Odd Alkyl Chain-Length Alternation Regulates Oligothiophene Crystal Structure. Author is Burnett, Edmund K.; Ai, Qianxiang; Cherniawski, Benjamin P.; Parkin, Sean R.; Risko, Chad; Briseno, Alejandro L..

Alkyl chains of varied length and steric bulk are generally appended to π-conjugated chromophores to increase solubility These alkyl chains also regulate many aspects of the solid-state packing and, in turn, resultant electronic and optical properties of organic semiconductors, yet there remains little understanding as to how these moieties govern such characteristics. Here, we report on a series of (2,5-bis(3-alkylthiophen-2-yl) thieno[3,2-b]thiophenes) (BTTT) monomers where the single-crystal packing configurations and m.ps. alternate as a function of whether the alkyl side chains have an even or odd number of carbon atoms. When the alkyl chains contain an even number of carbon atoms, the mols. predominantly crystallize with the BTTT units of the stacked lamellae aligned in the same direction. In contrast, when the number of carbon atoms is odd, alternating lamellae are twisted with respect to their neighbors, i.e. the BTTT moieties in one layer are aligned in an orthogonal-like fashion to those in its neighboring lamellae, and the crystal m.ps. tend to be higher than those with the even-numbered alkyl chains. With d. functional theory calculations and geometric analyses, the variations in crystal structure and thus the differences in phys. properties are rationalized by an oscillating interlayer interaction that is a function of alkyl side chain atom count and length. This study characterizes an extreme case of an organic semiconductor crystal packing alternation to highlight the effect of even-odd assembly as an underutilized and under-reported handle for tuning the mol. packing of organic semiconductor materials.

Compounds in my other articles are similar to this one(1-Bromoundecane)Formula: C11H23Br, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Synlett called Cobalt-Catalyzed Decarboxylative Methylation and Ethylation of Aliphatic N-(Acyloxy)phthalimides with Organoaluminum Reagents, Author is Wang, Ze-Zhong; Wang, Guang-Zu; Zhao, Bin; Shang, Rui; Fu, Yao, which mentions a compound: 693-67-4, SMILESS is CCCCCCCCCCCBr, Molecular C11H23Br, Safety of 1-Bromoundecane.

A cobalt-catalyzed decarboxylative methylation of aliphatic redox-active esters [N-(acyloxy)phthalimides; RAEs] I (R = heptadecyl, 1-[(4-methylphenyl)sulfonyl]piperidin-4-yl, 1-benzoylpyrrolidin-2-yl, 4-(4-chlorophenoxy)butyl, etc.) with trimethylaluminum under mild conditions was developed, providing a method for transforming a carboxylate group into a Me group without redox fluctuation. Primary and secondary RAEs I were both amenable substrates, whereas a tertiary RAE delivered an elimination product. Triethylaluminum was also used to deliver a decarboxylative ethylation product RC2H5.

Compounds in my other articles are similar to this one(1-Bromoundecane)Safety of 1-Bromoundecane, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Category: tetrahydroisoquinoline. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: 1-Bromoundecane, is researched, Molecular C11H23Br, CAS is 693-67-4, about Solvent Dependence of the Monomer-Dimer Equilibrium of Ketone-Substituted Triscatecholate Titanium(IV) Complexes. Author is Kwamen, A. Carel N.; Jenniches, Judith; Oppel, Iris M.; Albrecht, Markus.

Hierarchical helicates based on ketone-substituted titanium(IV)triscatecholates show different monomer-dimer behavior depending on different solvents. The dimerization constants of a whole series of differently alkyl-substituted complexes is analyzed to show that the solvent has a very strong influence on the dimerization. Hereby, effects like solvophobicity/philicity, sterics, electronics of the substituents and weak side-chain-side-chain interactions seem to act in concert.

Compounds in my other articles are similar to this one(1-Bromoundecane)Category: tetrahydroisoquinoline, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem

Rieth, Thorsten; Tober, Natalie; Limbach, Daniel; Haspel, Tobias; Sperner, Marcel; Schupp, Niklas; Wicker, Philipp; Glang, Stefan; Lehmann, Matthias; Detert, Heiner published an article about the compound: 1-Bromoundecane( cas:693-67-4,SMILESS:CCCCCCCCCCCBr ).Recommanded Product: 1-Bromoundecane. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:693-67-4) through the article.

Tristriazolotriazines with a threefold alkoxyphenyl substitution were prepared and studied by DSC, polarized optical microscopy (POM) and X-ray scattering. Six pentyloxy chains are sufficient to induce liquid-crystalline behavior in these star-shaped compounds Thermotropic properties of tristriazolotriazines with varying substitution patterns and a periphery of linear chains of different lengths, branching in the chain and swallow-tails, are compared. Generally, these disks display broad and stable thermotropic mesophases, with the tangential tristriazolotriazines being superior to the radial isomer. The structure-property relationships of the number of alkyl chains, their position, length and structure were studied.

Compounds in my other articles are similar to this one(1-Bromoundecane)Recommanded Product: 1-Bromoundecane, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Tetrahydroisoquinoline – Wikipedia,
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem