6-Methoxy-1,2,3,4-tetrahydroisoquinoline, cas is 42923-77-3, it is a common heterocyclic compound, the tetrahydroisoquinoline compound, its synthesis route is as follows.
2- [2- (3, 5-DIFLUORO-BENZYLCARBAMOYL)-PROPIONYLAMINO]-3- (LH-INDOL-3-YL)-PROPIONIC acid (64 mg, 0.15 mmol) was placed in a disposable polypropylene tube and dissolved in DMF (LML). TPTU (O- [2-OXO-1 (2H)-PYRIDYL]-N, N, N’, N’-tetramethyluronium- tetrafluoroborate, 49 mg, 0.165 mmol) and 6-METHOXY-1, 2,3, 4-tetrahydro-isoquinoline (24 mg, 0.15 mmol) were added, and the mixture was shaken overnight at r. t. The title compound, MS: m/e = 575.3 (M+H+), was isolated from the reaction mixture by automated, preparative HPLC (YMC CombiPrep C18 column 50 x 20 mm, solvent gradient 5-95 % CH3CN in 0.1 % TFA (aq) over 6.0 min, 230 nm, flow rate 40 ml/min).
42923-77-3, With the rapid development of chemical substances, we look forward to future research findings about 6-Methoxy-1,2,3,4-tetrahydroisoquinoline
Reference£º
Patent; F. HOFFMANN-LA ROCHE AG; WO2004/69826; (2004); A1;,
Tetrahydroisoquinoline – Wikipedia
1,2,3,4-Tetrahydroisoquinoline | C9H11N – PubChem